Gene interactions and pathways from curated databases and text-mining

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AHSA1 — RAC3

Text-mined interactions from Literome

Woo et al., Mol Cells 2002 (MAP Kinase Signaling System) : Rac GTPase activity is essential for lipopolysaccharide signaling to extracellular signal regulated kinase and p38 MAP kinase activation in rat-2 fibroblasts
Dunford et al., J Bone Miner Res 2006 : Paradoxically, although risedronate induces apoptosis of J774 macrophages by inhibiting protein prenylation, the p38 inhibitor SB203580 enhanced N-BP induced apoptosis, suggesting that Rac induced p38 activation partially suppresses the pro-apoptotic effect of N-BPs in these cells
Shifrin et al., Biochem J 2012 (Mechanotransduction, Cellular) : Apoptosis was mediated by Rac dependent activation of p38a