Gene interactions and pathways from curated databases and text-mining

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RASA1 — RHO

Text-mined interactions from Literome

Gratzinger et al., FASEB J 2003 : We found that endothelial cells lacking PECAM-1 exhibit increased single cell motility and extension formation but poor wound healing migration, reminiscent of cells in which Rho activity has been suppressed by overexpressing a GTPase activating protein ( 3 )
Nur-E-Kamal et al., Mol Biol Cell 1992 : The GAP1 ( also called Ras GAP ) is highly specific for Ras and does not stimulate the intrinsic GTPase activity of Rap1 or Rho
Sanz-Moreno et al., Cell 2008 (Melanoma) : Conversely, in amoeboid movement, Rho-kinase signaling activates a Rac GAP , ARHGAP22, that suppresses mesenchymal movement by inactivating Rac
Reid et al., J Biol Chem 1996 : In addition, this peptide inhibited both endogenous and GTPase activating protein stimulated Rho GTPase activity