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RASA1 — RHO
Text-mined interactions from Literome
Gratzinger et al., FASEB J 2003
:
We found that endothelial cells lacking PECAM-1 exhibit increased single cell motility and extension formation but poor wound healing migration, reminiscent of cells in which
Rho activity has been
suppressed by overexpressing a
GTPase activating protein ( 3 )
Nur-E-Kamal et al., Mol Biol Cell 1992
:
The
GAP1 ( also called Ras GAP ) is highly specific for Ras and does not
stimulate the intrinsic GTPase activity of Rap1 or
Rho
Sanz-Moreno et al., Cell 2008
(Melanoma) :
Conversely, in amoeboid movement,
Rho-kinase signaling
activates a Rac
GAP , ARHGAP22, that suppresses mesenchymal movement by inactivating Rac
Reid et al., J Biol Chem 1996
:
In addition, this peptide inhibited both endogenous and
GTPase activating protein stimulated
Rho GTPase activity