We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to CREB3

CREB3 — RCAN1

Text-mined interactions from Literome

Kim et al., J Biol Chem 2011 (Down Syndrome) : In this report, we found that the regulator of calcineurin 1 (RCAN1) , which is overexpressed in the brain of patients with Down syndrome, increased the phosphorylation of CREB and cAMP response element mediated gene transcription in response to the activation of the intracellular cAMP pathway ... Furthermore, we found that the increased activation of CREB signaling by RCAN1 depended on the ability of RCAN1 to inhibit calcineurin activity ... Our data provide the first evidence that RCAN1 acts as an important regulatory component in the control of CREB signaling
Kim et al., J Cell Biochem 2013 : In contrast, RCAN1 significantly enhanced the activity of cAMP response element binding protein ( CREB ) ... In contrast, RCAN1 significantly enhanced the activity of cAMP response element binding protein ( CREB ) ... Furthermore, RCAN1 induced the expression of the CREB target gene, Bcl-2 ... Furthermore, RCAN1 induced the expression of the CREB target gene, Bcl-2