Roopra et al., Mol Cell Biol 2000
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Furthermore, we show that REST/NRSF binds mammalian SIN3A and HDAC-2 and requires histone deacetylase activity to repress neuronal gene transcription in both nonneuronal and neuronal cell lines
Battaglioli et al., J Biol Chem 2002
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Previous studies have shown that REST mediated repression requires histone deacetylase activity and that recruitment of deacetylases is mediated by two co-repressors, Sin3A and CoREST