Gene interactions and pathways from curated databases and text-mining

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NOX4 — RHOA

Text-mined interactions from Literome

Kim et al., J Biol Chem 2004 : However, purified prenylated recombinant RhoA did not activate NADPH oxidase in vitro, suggesting that Rho does not interact directly with NADPH oxidase
Sugimoto et al., Cardiovasc Res 2009 : Blockade of LOX-1 or MT1-MMP prevented RhoA dependent endothelial NO synthase protein downregulation and cell invasion, Rac1 mediated NADPH oxidase activity, and reactive oxygen species generation
Zhang et al., Antioxid Redox Signal 2010 : Maximal RhoA activation ( 1 min ) was inhibited by ROS scavenge or NADPH oxidase inhibition