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RHOA — TNFRSF1B
Text-mined interactions from Literome
Yamashita et al., Neuron 1999
:
In transfected cells,
p75NTR activated
RhoA , and neurotrophin binding abolished RhoA activation
Gehler et al., J Neurosci 2004
:
p75 neurotrophin receptor signaling
regulates growth cone filopodial dynamics through modulating
RhoA activity ... Furthermore,
p75NTR regulates
RhoA activity to mediate filopodial dynamics
Al-Gayyar et al., PloS one 2013
(Diabetes Mellitus, Experimental...) :
Taken together, these results provide compelling evidence for a causal role of proNGF in diabetes induced retinal neurodegeneration through enhancing
p75 ( NTR ) expression and direct
activation of
RhoA and p38MAPK/JNK apoptotic pathways