Gene interactions and pathways from curated databases and text-mining

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RHOA — TNFRSF1B

Text-mined interactions from Literome

Yamashita et al., Neuron 1999 : In transfected cells, p75NTR activated RhoA , and neurotrophin binding abolished RhoA activation
Gehler et al., J Neurosci 2004 : p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity ... Furthermore, p75NTR regulates RhoA activity to mediate filopodial dynamics
Al-Gayyar et al., PloS one 2013 (Diabetes Mellitus, Experimental...) : Taken together, these results provide compelling evidence for a causal role of proNGF in diabetes induced retinal neurodegeneration through enhancing p75 ( NTR ) expression and direct activation of RhoA and p38MAPK/JNK apoptotic pathways