Gene interactions and pathways from curated databases and text-mining

◀ Back to S100A8

RUNX3 — S100A8

Text-mined interactions from Literome

Tsang et al., Oncogene 2010 (Helicobacter Infections...) : In this study, we show that H. pylori infection inactivates the gastric tumor suppressor RUNX3 in a CagA dependent manner
Liu et al., J Cell Biochem 2012 (MAP Kinase Signaling System) : Helicobacter pylori CagA inhibits the expression of Runx3 via Src/MEK/ERK and p38 MAPK pathways in gastric epithelial cell ... Luciferase reporter assay was used to determine the effects of CagA on the 1,150 bp promoter activity of Runx3 ... Signal inhibitors were used to detect the signal pathway ( s ) through which CagA affects Runx3 ... Our results showed that CagA can reduce the expression level of Runx3 at both mRNA and protein levels significantly