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IGF1 — SGK1

Text-mined interactions from Literome

Kobayashi et al., Biochem J 1999 : Our results are consistent with a model in which activation of SGK by IGF-1 or hydrogen peroxide is initiated by a PtdIns ( 3,4, 5 ) P3-dependent activation of PDK2, which phosphorylates Ser422
Perrotti et al., J Biol Chem 2001 : Insulin and insulin-like growth factor-1 stimulate activity of Sgk by a mechanism mediated by phosphoinositide dependent kinases ( PDK)-1 and -2
Palmada et al., Biochem Biophys Res Commun 2005 : As SGK1 , 3 and PKB are activated by insulin and IGF1 , the described mechanisms presumably participate in the hormonal stimulation of cellular amino acid uptake
Xu et al., J Biol Chem 2005 (Hypertension) : Finally, we show that WNK1 is required for the activation of SGK1 by insulin-like growth factor 1
Cheng et al., Circ Res 2010 (Carotid Artery Injuries...) : SGK-1 activation in response to stretch is blocked by insulin-like growth factor (IGF)-1 receptor inhibitor and mammalian target of rapamycin complex ( mTORC)2 inhibitor ( Ku-0063794 ) but not mTORC1 inhibitor ( rapamycin )