Wang et al., American journal of physiology. Renal physiology 2001
:
In A6 kidney cells, mineralocorticoid induction of the phosphorylated form of SGK preceded the increase in Na+ transport, and specific inhibition of PI3K inhibited both phosphorylation of SGK and mineralocorticoid induced Na+ transport
Yan et al., Biochem J 2008
:
The activation of the AGC ( protein kinase A/protein kinase G/protein kinase C ) -family kinase SGK1 ( serum- and glucocorticoid induced kinase 1 ) by insulin via PI3K ( phosphoinositide 3-kinase ) signalling has been appreciated for almost 10 years
Miller et al., Breast Cancer Res 2011
(Breast Neoplasms...) :
PI3K activates AKT, serum/glucocorticoid regulated kinase ( SGK ), phosphoinositide dependent kinase 1 ( PDK1 ), mammalian target of rapamycin (mTOR), and several other molecules involved in cell cycle progression and survival