Gene interactions and pathways from curated databases and text-mining

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MAPK15 — SLC9A1

Text-mined interactions from Literome

Pedersen et al., Cell Physiol Biochem 2007 (Carcinoma, Ehrlich Tumor) : Shrinkage-activation of p38 MAPK was NHE1 independent, and p38 MAPK inhibition ( SB203580 ) attenuated NHE1 activation and ERK1/2 inhibition
Garciarena et al., Cell Physiol Biochem 2011 (Myocardial Reperfusion Injury) : In line with the fact that ROS induce MAPK mediated NHE-1 activation, myocardial infarction increased ERK1/2, p90 ( RSK ), and NHE-1 phosphorylation
Aharonovitz et al., J Biol Chem 1996 : We propose that the MAPK activation of the NHE-1 does not involve phosphorylation of this exchanger protein
Bianchini et al., J Biol Chem 1997 : Whereas p44 MAPK does not appear to phosphorylate NHE1 in vitro, we found that inhibition of the p42/p44 MAPK signaling by expression of a dominant negative form of p44 MAPK, by expression of the MAP kinase phosphatase MKP-1, or by inhibition of MAPK kinase 1 (MKK1) with the PD 98059 compound reduced by 50-60 % NHE1 activation in response to growth factors