Gene interactions and pathways from curated databases and text-mining

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SOX17 — TCF25

Text-mined interactions from Literome

Passeron et al., Proc Natl Acad Sci U S A 2007 : During melanocyte development from the neural crest, SOX10 regulates microphthalmia associated transcription factor , which controls a set of genes critical for pigment cell development and pigmentation, including dopachrome tautomerase and tyrosinase ... In adult and neonatal melanocytes, SOX9 regulates microphthalmia associated transcription factor , dopachrome tautomerase, and tyrosinase promoters, leading to an increase in the expression of these key melanogenic proteins and finally to a stimulation of pigmentation
Sinner et al., Mol Cell Biol 2007 (Carcinoma...) : When overexpressed in SW480 colon carcinoma cells, Sox17 represses beta-catenin/TCF activity in a dose dependent manner and inhibits proliferation
Chen et al., Liver Int 2013 (Carcinoma, Hepatocellular...) : In addition, SOX4 in HepG2 cell can enhance ß-catenin/TCF activity by increasing ß-catenin level