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CDK1 — SP1
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Lu et al., Mol Endocrinol 2000
(Adenocarcinoma...) :
Androgen induction of
cyclin dependent kinase inhibitor p21 gene :
role of androgen receptor and transcription factor
Sp1 complex
PeƱuelas et al., Eur J Biochem 2003
:
The expression of the transcription factor
Sp1 , a retinoblastoma interacting protein, was also
enhanced by all the
cyclin dependent kinase inhibitors tested
Chang et al., Proc Natl Acad Sci U S A 2004
:
We previously reported that
Sp1 dependent
Cdc2 gene expression is inhibited by tetra-O-methyl nordihydroguaiaretic acid ( M ( 4 ) N ) and that M ( 4 ) N is likely responsible for causing growth arrest in M ( 4 ) N-treated transformed C3 cells
Sun et al., J Thorac Oncol 2011
(Carcinoma, Non-Small-Cell Lung...) :
Terameprocol down-regulates the
Sp1 mediated transcription of survivin and
Cdk1 , which is important for cell cycle progression and many other proteins
Chew et al., J Biol Chem 2012
:
Sulforaphane induction of p21 ( Cip1 )
cyclin dependent kinase inhibitor expression
requires p53 and
Sp1 transcription factors and is p53 dependent