Gene interactions and pathways from curated databases and text-mining

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ICAM1 — SP1

Text-mined interactions from Literome

Pazdrak et al., Gastroenterology 2004 : TNFalpha suppresses human colonic circular smooth muscle cell contractility by SP1- and NF-kappaB mediated induction of ICAM-1
Yang et al., Arterioscler Thromb Vasc Biol 2005 (Myocardial Reperfusion Injury) : We examined the roles of Stat and Sp1 in the regulation of ICAM-1 after myocardial I-R ... Sp1 coimmunoprecipitated with p-S727 Stat3 during H-R, and Sp1 or Stat3alpha interfering RNA markedly reduced ICAM-1 mRNA expression
Tung et al., J Biomed Sci 2012 (Colonic Neoplasms) : Inhibition of Sp1 , C/EBP-ß and NF-?B activations by specific siRNA blocked the SDF-1 induced ICAM-1 promoter activity and expression