Gene interactions and pathways from curated databases and text-mining

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FGF2 — SPARC

Text-mined interactions from Literome

Shiba et al., Dev Biol 1995 : Effects of basic fibroblast growth factor on proliferation, the expression of osteonectin ( SPARC ) and alkaline phosphatase, and calcification in cultures of human pulp cells ... In this study, we examined the effects of bFGF on DNA synthesis, osteonectin/SPARC levels, alkaline phosphatase ( ALPase ) activity, their mRNA levels, and calcium levels in cultures of human pulp cells ... The effects of bFGF on ALPase activity and SPARC synthesis were reversible
Pichler et al., Am J Pathol 1996 (Glomerulonephritis) : We now show that SPARC is synthesized by mesangial cells in culture and that SPARC mRNA levels are increased by platelet derived growth factor and basic fibroblast growth factor
Damjanovski et al., Dev Genes Evol 1998 : While basic fibroblast growth factor (bFGF) , a ventral mesoderm inducer, had modest effects on SPARC mRNA expression, the combination of both activin and bFGF was synergistic
Delany et al., Am J Physiol 1998 : We used the murine osteoblastic cell line MC3T3 to determine whether basic FGF (bFGF) regulates osteonectin expression in bone