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HIF1A — SPP1

Text-mined interactions from Literome

Colla et al., Blood 2007 (Multiple Myeloma...) : In turn, we show that the inhibition of HIF-1alpha by siRNA suppressed IL-8 and OPN production by MM cells under hypoxia
Song et al., Cancer Sci 2008 (Disease Progression...) : Osteopontin promotes ovarian cancer progression and cell survival and increases HIF-1alpha expression through the PI3-K/Akt pathway ... Furthermore, we also found that inhibition of the PI3-K/Akt pathway attenuated OPN mediated HIF-1alpha up-regulation in ovarian cancer cells
Song et al., J Cell Mol Med 2009 (Neoplasm Invasiveness...) : Further study shows that OPN activated phosphoinositide 3-kinase/Akt survival pathway and up-regulated HIF-1alpha via binding to v3 integrins in gastric cancer cells