Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — SPP1

Text-mined interactions from Literome

Li et al., J Appl Physiol 2004 (Anoxia) : In contrast, FGF-1 induced OPN expression was blocked by inhibitors of JNK or MEK1/2 but not of PI3K , p70S6K, or p38MAPK
Shao et al., Carcinogenesis 2007 (Adenocarcinoma...) : Moreover, OPN expression was strongly increased in Ras induced transformation of intestinal epithelial cells in a PI3K dependent manner
Dai et al., Oncogene 2009 : Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells