Gene interactions and pathways from curated databases and text-mining

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MMP12 — SRC

Text-mined interactions from Literome

Razandi et al., J Biol Chem 2003 (Breast Neoplasms) : This resulted from Src induced MMP activation , implicated using PP2 ( Src family kinase inhibitor ) or the expression of a dominant negative Src protein
Martinez-Orozco et al., Eur J Cell Biol 2010 (Neoplasm Invasiveness) : We demonstrate here that AA promotes an increase in vimentin and N-cadherin expression, MMP-9 secretion, a decrease in E-cadherin junctional levels, and the activation of FAK, Src and NF-kappaB in MCF10A cells