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IL3 — STAT3

Text-mined interactions from Literome

Steinman et al., Leukemia 1999 (Cell Transformation, Neoplastic) : We report that IL-3 inhibited the ability of G-CSF to induce Stat3 DNA binding
O'Brien et al., J Biol Chem 1999 : STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130 utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroid hormone
Iwamoto et al., Cytokine 2004 (Leukemia, Myeloid, Acute) : Stat3 dependent induction of interleukin-3 receptor expression in leukemia inhibitory factor stimulated M1 mouse leukemia cells
Dillon et al., Leuk Res 2008 (Polycythemia Vera...) : Western blot analysis showed an increase in Tpo and IL-3 induced Stat3 and Stat5 tyrosine phosphorylation in BaF3/Mpl and BaF3 cells expressing Prv-1
Ozawa et al., Journal of ophthalmology 2011 : In innate chorioretinal inflammation, interleukin-6 family ligands induce STAT3 activation in photoreceptors, which causes UPS mediated excessive degradation of the visual substance, rhodopsin
Kandala et al., Drug Discov Ther 2012 (Ovarian Neoplasms) : IL-3 induced phosphorylation of JAK2 and STAT3 was significantly blocked by DIM
Mu et al., Blood 1995 : Both MGDF and IL-3 induce tyrosine phosphorylation of STAT3 ( APRF ) and STAT5 ( MGF ), with MGDF favoring STAT3 while IL-3 predominantly causes STAT5 phosphorylation
Nagata et al., Biochem Biophys Res Commun 1996 : Interleukin 3 activates not only JAK2 and STAT5, but also Tyk2, STAT1, and STAT3 ... Furthermore, we found that IL3 induces activation of not only STAT5 but also STAT1 and STAT3
Kirito et al., J Biol Chem 1997 : This indicates that IL-3 , GM-CSF, and EPO commonly activated Stat1alpha, Stat3 , and Stat5 proteins in UT-7 ... Thus, although Stat1alpha, Stat3 , and Stat5 proteins are activated by GM-CSF, IL-3 , and EPO, our data suggest that each STAT protein has a distinctive role in the actions of cytokines
Chaturvedi et al., Oncogene 1998 : Expression of a dominant negative mutant of src ( AMSrc ) in these cells results in a block to IL-3 mediated phosphorylation of STAT-3 , and its ability to bind to DNA ... On the other hand, expression of a dominant negative mutant of JAK2 ( JAK2KE ) had no effect on IL-3 mediated activation of STAT-3