◀ Back to BCL2

BCL2 — STAT5A

Text-mined interactions from Literome

Dumon et al., Oncogene 1999 : IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line
Gesbert et al., Blood 2000 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : We found that the proviability protein Bcl-X ( L ), but not Bcl-2 , was induced by both p210 ( Bcr/Abl ) and STAT5-1*6
Shelburne et al., Mol Immunol 2002 : The absence of Stat5 resulted in aberrant control of Bcl-2 , Bcl-x ( L ) and cyclin A2, with increased apoptosis and delayed cell cycle progression after IL-3 or SCF stimulation
Versteeg et al., Circ Res 2004 : In conclusion, our results show that FVIIa induces cell survival through STAT5 dependent Bcl ( XL ) production and Jak2 dependent activation of PKB
Bhattacharyya et al., J Biol Chem 2007 (Neoplasms) : Curcumin prevents tumor induced T cell apoptosis through Stat-5a mediated Bcl-2 induction
Rochman et al., J Immunol 2008 (Lymphopenia) : We now demonstrate that CD8 ( + ) T cells express TSLPR and that TSLP activates both STAT5 and Akt and induces Bcl-2 in these cells
Marrero et al., Brain Res 2009 (Inflammation) : In this study, we investigated the effects of inhibiting the alpha7 nAChR-JAK2 pro-survival cascade on the nicotine induced production of the survival factor Bcl-2 and the transcriptional activation of NF-kappaB, AP-1, STAT1, STAT3, and STAT5
Qian et al., Biochim Biophys Acta 2009 (Glioma) : To determine whether Stat5 regulates Bcl-xL expression in CAM induced cell death, C6-glioma was infected with an adenovirus containing a constitutively activated Stat5-GFP ( Ad-Stat5ca ) ... Overexpression of Stat5ca increased Bcl-xL and decreased CAM induced cell death compared to control adenovirus infected cells ; whereas Stat5 siRNA decreased DX-induced Bcl-xL and increased cell death