Gene interactions and pathways from curated databases and text-mining

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MUC1 — SYT1

Text-mined interactions from Literome

Ahmad et al., Cancer Res 2009 : These findings indicate that MUC1-C is a direct activator of NF-kappaB p65 and that an inhibitor of MUC1 function is effective in blocking activation of the NF-kappaB pathway
Yin et al., Mol Pharmacol 2010 (Multiple Myeloma) : Inhibition of MUC1-C function also blocked the interaction between MUC1-C and NF-kappaB p65 and activation of the NF-kappaB pathway
Cascio et al., J Biol Chem 2011 (Adenocarcinoma...) : MUC1 protein expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-?B p65 and binding to cytokine promoters : importance of extracellular domain