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MUC1 — SYT1
Text-mined interactions from Literome
Ahmad et al., Cancer Res 2009
:
These findings indicate that
MUC1-C is a direct
activator of NF-kappaB
p65 and that an inhibitor of MUC1 function is effective in blocking activation of the NF-kappaB pathway
Yin et al., Mol Pharmacol 2010
(Multiple Myeloma) :
Inhibition of
MUC1-C function also
blocked the interaction between MUC1-C and NF-kappaB
p65 and activation of the NF-kappaB pathway
Cascio et al., J Biol Chem 2011
(Adenocarcinoma...) :
MUC1 protein expression in tumor cells
regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-?B
p65 and binding to cytokine promoters : importance of extracellular domain