Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — TAT

Text-mined interactions from Literome

Myou et al., J Immunol 2003 (MAP Kinase Signaling System) : TAT-Deltap85 and LY294002, a PI3K inhibitor , blocked the phosphorylation of gIV-PLA(2) at Ser ( 505 ) caused by fMLP, thus inhibiting gIV-PLA(2) hydrolysis and production of AA and LTC ( 4 ) in eosinophils
Zhou et al., PloS one 2013 (Cell Transformation, Neoplastic...) : Mechanistic studies indicated Tat activates PI3K and AKT, and inactivates PTEN and GSK-3ß in vIL-6 expressing cells
Milani et al., AIDS 1998 : Extracellular Tat induced a rapid increase of p125FAK tyrosine phosphorylation and p125FAK associated PI 3-K activity