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PIK3R1 — TAT
Text-mined interactions from Literome
Myou et al., J Immunol 2003
(MAP Kinase Signaling System) :
TAT-Deltap85 and LY294002, a
PI3K inhibitor , blocked the phosphorylation of gIV-PLA(2) at Ser ( 505 ) caused by fMLP, thus inhibiting gIV-PLA(2) hydrolysis and production of AA and LTC ( 4 ) in eosinophils
Zhou et al., PloS one 2013
(Cell Transformation, Neoplastic...) :
Mechanistic studies indicated
Tat activates
PI3K and AKT, and inactivates PTEN and GSK-3ß in vIL-6 expressing cells
Milani et al., AIDS 1998
:
Extracellular
Tat induced a rapid increase of p125FAK tyrosine phosphorylation and p125FAK associated
PI 3-K activity