Gene interactions and pathways from curated databases and text-mining

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CCL2 — TCF21

Text-mined interactions from Literome

Zhou et al., Circ Res 2006 (Myocardial Ischemia...) : Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction ... We present evidence that MCP-1 binding to CCR2 induces a novel transcription factor ( MCP induced protein [ MCPIP ] ) that causes cell death
Küper et al., Mediators Inflamm 2012 : Recent studies suggest that in kidney cells osmolality induced MCP-1 upregulation is mediated by the osmosensitive transcription factor , nuclear factor of activated T cells 5 ( NFAT5 )
Bethel-Brown et al., Journal of neuroinflammation 2012 (HIV Infections) : MCP-1 induction was regulated by activation of extracellular-signal regulated kinase ( ERK ) 1/2, c-Jun N-terminal kinase (JNK) and p38 mitogen activated protein ( MAP ) kinases and phosphatidylinositol 3-kinase (PI3K)/Akt pathways and the downstream transcription factor , nuclear factor ?B ( NF?B )