Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — TCF23

Text-mined interactions from Literome

Smith et al., J Biol Chem 2005 : Furthermore, DEX mediated inhibition of LEF/TCF transcriptional activity was attenuated in the presence of dominant negative forms of either PI3K or protein kinase B/Akt
Belaiba et al., Mol Biol Cell 2007 (Anoxia) : Furthermore, inhibition of the phosphatidylinositol 3-kinase (PI3K)/AKT but not extracellular signal regulated kinase 1/2 pathway blocked the hypoxia dependent induction of HIF-1alpha mRNA and HIF-1alpha promoter activity, suggesting involvement of a PI3K/AKT regulated transcription factor
Kim et al., J Immunol 2007 (Asthma...) : Our results also showed that PI3K inhibitors or AdPTEN down-regulated a transcription factor , NF-kappaB activity, and BAY 11-7085 substantially reduced the increased levels of IL-17 after TDI inhalation
Banerjee et al., Endocrinology 2009 : Downstream of ERK1/2, CG activates the nuclear transcription factor , Elk1, also in a PI3K-MAPK dependent manner
Sonderegger et al., Endocrinology 2010 : Chemical inhibition of PI3K abolished Wnt dependent phosphorylation of AKT and GSK-3beta and trophoblast motility but did not affect appearance of activated beta-catenin or Wnt/TCF reporter activity
Yen et al., J Biol Chem 2011 (MAP Kinase Signaling System) : PKA, PI3K , and ERK inhibitors abolished PGE2- and cAMP induced c-Fos and MMP-9 up-regulation, and ERK activation was required for the binding of activator protein 1 (AP-1) transcription factor to the MMP-9 promoter