Gene interactions and pathways from curated databases and text-mining

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ICAM1 — TCF25

Text-mined interactions from Literome

Lawson et al., J Immunol 1999 : ICAM-1 cross linking caused activation of Erk-1 and the AP-1 transcription factor complex, without any increase in NF-kappaB activity, in contrast to TNF stimulation
Hoffmann et al., Clin Exp Immunol 1999 : Since PDTC is known to be a potent inhibitor of NF-kappaB, the stimulating effects of neopterin on ICAM-1 gene expression and protein generation may be mediated by activation of this transcription factor
Hess et al., Stroke 2000 (Reperfusion Injury) : We determined whether a NF-kappaB transcription factor decoy ( TFD ) could block intercellular adhesion molecule (ICAM)-1 upregulation, an indicator of endothelial cell activation
Blaber et al., J Am Soc Nephrol 2003 : Only AP-1 activation, however, was calcium dependent, suggesting the central involvement of this transcription factor in ICAM-1 and RANTES induction after the ligation of ICAM-1
Ishihara et al., Dig Dis Sci 2006 : ICAM-1 expression, stimulated by neutrophil elastase, was partially reduced by a diacylglycerol kinase inhibitor and protein kinase C inhibitor, but was completely inhibited by a phospholipase C inhibitor, cytosolic Ca ( 2+ ) chelator, calmodulin antagonist, and nuclear transcription factor kappa B inhibitor
Sun et al., International journal of biological sciences 2008 : The expression of HO-1, iNOS ( Western blot ) and ICAM-1 ( cell ELISA ) proteins and activation of inflammation-relevant transcription factor , NF-kappaB ( EMSA ) were assessed
Grether-Beck et al., Proc Natl Acad Sci U S A 1996 : Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen induced expression of the human intercellular adhesion molecule 1 gene
Jaeschke et al., Hepatology 1999 (Endotoxemia...) : However, there was no significant difference in other critical parameters, e.g., activation of the transcription factor , nuclear factor-kappaB (NF-kappaB), and soluble intercellular adhesion molecule-1 ( sICAM-1 ), parenchymal cell apoptosis, and neutrophil sequestration in the liver