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LEP — TCF4

Text-mined interactions from Literome

Scarpace et al., Neuropharmacology 2000 (Obesity) : In addition, the leptin induced increase in P-STAT3 transcription factor binding was diminished in aged rats ... In addition, aged, overweight rats demonstrate reduced signal transduction in response to leptin, with reduced sensitivity for STAT3 phosphorylation and diminished leptin induced P-STAT3 transcription factor binding
Scarpace et al., Physiol Behav 2001 (Obesity) : Leptin induced P-STAT3 levels and P-STAT3 transcription factor binding were diminished with age
Stepanyan et al., J Neuroendocrinol 2003 : With double labelling immunohistochemistry, we studied the colocalization of leptin activated transcription factor , STAT3, with somatostatin receptor subtypes, sst1, sst2A, sst2B, sst3 and sst4, or the neuropeptide itself, in the rat hypothalamus
Fox et al., Frontiers in bioscience : a journal and virtual library 2007 : Evidence from our laboratory suggests that Nescient helix-loop-helix 2 (Nhlh2) regulates the transcription of PC1 and PC2, possibly in conjunction with the leptin stimulated transcription factor , STAT3
Tups et al., J Neuroendocrinol 2009 : In this state, leptin induced phosphorylation of the important transcription factor , signal transducer and activator of transcription 3 ( STAT3 ), is impaired in the arcuate nucleus and the ventromedial hypothalamus ( only during pregnancy )