Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — TGFB2

Text-mined interactions from Literome

Higaki et al., Arterioscler Thromb Vasc Biol 1999 : We also found that transforming growth factor-beta stimulated PI3K activity and the phosphorylation of Akt, a downstream signaling molecule of PI3K
Kang et al., Dev Dyn 2002 : Phosphatidylinositol-3 (PI-3) kinase regulates cytoskeleton reorganization, cell migration, and transforming growth factor ( TGF ) beta regulated EMT
Yao et al., Ophthalmic Res 2008 : TGF-beta2 activated PI3K/Akt in a time dependent manner, but not extracellular signal regulated kinase and p38 MAPK
Veillette et al., Biol Reprod 2013 : PI3-K inhibition in vivo blocked Akt phosphorylation, reduced Smad2 phosphorylation, and reduced both TGF-beta2 and XIAP expression