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EGF — TGFBR2
Text-mined interactions from Literome
Zieske et al., Invest Ophthalmol Vis Sci 2001
:
To determine the
effect of
epidermal growth factor (EGF) and TGF-beta1 on p15(INK4b) and
TbetaR-I and -II expression, human corneal epithelial cells were grown in culture to 50 % to 60 % confluence, and EGF ( 5 ng/ml ) and/or TGF-beta1 ( 2 ng/ml ) were added for 6 hours ... In cultured cells,
EGF and TGF-beta1
stimulated TbetaR-II ; however, neither one stimulated TbetaR-I expression
Song et al., J Biol Chem 2006
(Prostatic Neoplasms) :
We have also shown that changes in
TbetaRII levels by EGF are
EGF receptor-kinase
dependent and are controlled by signals downstream of MEK1/2
Schluns et al., Int Immunol 1995
:
In vitro,
epidermal growth factor (EGF)
increases transcript levels of TGF-beta 1, TGF-beta 3 and
T beta RII , suggesting that EGF may modulate TGF-beta responses in TEC ; however, TGF-beta 2 and T beta RI transcript levels were not affected