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IL7 — TNFSF11

Text-mined interactions from Literome

Toraldo et al., Proc Natl Acad Sci U S A 2003 (Bone Resorption) : Importantly, T cell adoptive transfer into nude mice restored IL-7 induced bone loss, and RANKL and TNF-alpha secretion, demonstrating that T cells are essential mediators of IL-7 induced bone loss in vivo
Kim et al., J Immunol 2005 : We found that IL-7 signaling through the common cytokine receptor gamma-chain was critical for the optimal expression of both TNF related activation induced cytokine and CD30L but not OX40L
Lee et al., Exp Mol Med 2008 : RANKL stimulates proliferation, adhesion and IL-7 expression of thymic epithelial cells
Gendron et al., Immunology 2008 : Furthermore, we found that simultaneous activation of effector CD4 ( + ) T cells via alpha1beta1 integrin and IL-7R synergistically increases the production of RANKL and enhances their osteoclastogenic function
Zheng et al., Biochem Pharmacol 2013 (Bone Resorption) : Coumermycin A1 also abrogated RANKL induced expression of interleukin-1ß , tumor necrosis factor-a, and inducible nitric oxide synthase in mouse BMMs. Consistent with the in vitro anti-osteoclastogenic effect, the aminocoumarin suppressed lipopolysaccharide induced osteoclast formation and bone loss in in vivo mouse experiments