Gene interactions and pathways from curated databases and text-mining

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IFNG — TNFSF13B

Text-mined interactions from Literome

Moore et al., Science 1999 : BLyS expression on human monocytes could be up-regulated by interferon-gamma
Nardelli et al., Blood 2001 : The expression of BLyS on monocyte membranes was retained following differentiation into macrophages, but detection on the surface of monocyte derived dendritic cells required stimulation with IFN-gamma ... Both IFN-gamma and IL-10 enhanced the release of soluble BLyS that was active in B-cell proliferation assays
Alsaleh et al., Arthritis Rheum 2007 (Arthritis, Rheumatoid) : Moreover, we found that IFNgamma induced BAFF synthesis is inhibited by simultaneous stimulation with either TLR ligands or TNFalpha ... In contrast, we demonstrated that stimulation of alpha5beta1 integrin can induce BAFF synthesis and release per se and that stimulation of this pathway has no inhibitory effect on IFNgamma induced BAFF synthesis
Reyes et al., Cytokine 2008 (Arthritis, Rheumatoid) : Moreover, Dex suppressed both mRNA and protein BAFF expression induced by TNF-alpha but had no effect on IFN-gamma induced BAFF expression
Kim et al., J Leukoc Biol 2008 : In the present study, we examined the pathways by which TGF-beta1 and IFN-gamma induce BAFF expression to see if TGF-beta1 and IFN-gamma regulate B cell differentiation via macrophages ... IFN-gamma further augmented TGF-beta1 induced BAFF expression ... IFN-gamma caused phosphorylation of CREB, and overexpression of CREB increased IFN-gamma induced BAFF promoter activity ... Neither Stat1alpha ( a well-known transducing molecule of IFN-gamma ) nor AG490 ( a JAK inhibitor ) affected BAFF expression in response to IFN-gamma
Jiang et al., Eur J Haematol 2009 (Multiple Myeloma) : We also found that IFN-gamma and IL-6 can induce BLyS expression on MM cells, while after the treatment of BAY11-7082, an IkB-alpha phosphorylation inhibitor, IFN-gamma induced up regulation of BLyS was completely inhibited, suggesting that nuclear factor kappaB (NF-kappaB) might be involved in the mechanism of the regulation of BLyS levels in response to cytokines
Parameswaran et al., Clin Immunol 2009 (Lupus Erythematosus, Systemic) : In addition, IFN-gamma and IL-10, which induce BAFF secretion, were down-regulated in hCDR1 treated mice
Tarantino et al., J Viral Hepat 2009 (Hepatitis C...) : BLyS/BAFF expression by macrophages is stimulated by interferon-gamma and interleukin-10, and its serum levels are increased in chronic hepatitis C ( CHC )
Zhu et al., Blood 2009 (Purpura, Thrombocytopenic, Idiopathic) : The effects of recombinant human BAFF ( rhBAFF ) and BAFF-R-Fc fusion protein ( BR3-Fc ) on B cells, T cells, platelets, secretion of interferon gamma (IFNgamma) , and interleukin-4 (IL-4) were measured by flow cytometry and ELISA