Gene interactions and pathways from curated databases and text-mining

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FGF8 — TNP2

Text-mined interactions from Literome

Takechi et al., Neurol Med Chir (Tokyo) 1994 (Neovascularization, Pathologic...) : TNP did not completely suppress laminin or basic FGF expression
Fujimoto et al., Nihon Sanka Fujinka Gakkai Zasshi 1996 (Neoplasm Invasiveness...) : TNP470 , a inhibitor of vessel endothelial proliferation, inhibited directly basic FGF in the PD
Fujimoto et al., Cancer Lett 1997 (Endometrial Neoplasms) : To know the potential of growth, invasion and metastasis of endometrial cancer associated with neovascularization, the effects of sex steroids and O- ( chloroacetyl-carbamoyl ) fumagillol ( TNP-470 ; AGM-1470 ) on basic fibroblast growth factor (FGF) expression and secretion and its mRNA expression were investigated in well differentiated endometrial cancer cell line Ishikawa and in undifferentiated endometrial cancer cell line AN3 CA. Basic FGF expression and secretion and its mRNA expression in Ishikawa cells, but not in AN3 CA cells, were increased by estrogen, while progesterone diminished the estrogen induced increases ... Therefore, basic FGF secretion may be inhibited by progestin in differentiated cells, and by TNP-470 in undifferentiated cells