◀ Back to NFKB1

NFKB1 — TOP1

Text-mined interactions from Literome

Lambert et al., J Nutr 2003 (Neoplasms) : Studies with human cancer cell lines have demonstrated that epigallocatechin-3-gallate ( EGCG ), a major tea polyphenol, inhibits mitogen activated protein kinases, cyclin dependent kinases, growth factor related cell signaling, activation of activator protein 1 (AP-1) and nuclear factor kappaB (NFkappaB) , topoisomerase I and matrix metalloproteinases as well as other potential targets
Lin et al., Anticancer Res 2005 (Stomach Neoplasms) : It was shown that ( - ) -Menthol inhibited the proliferation of the cells in a dose- and time dependent manner, inhibited topoisomerase I , IIa and IIbeta, but promoted the levels of NF-kappaB gene expression based on the Western blot and polymerase chain reaction ( PCR ) and cDNA microarray methods
Xu et al., Cancer Chemother Pharmacol 2009 (Neoplasms) : Based on the preclinical evidence of topoisomerase I ( Topo-1 ) upregulation by mitomycin C ( MMC ) and decreased NF-kappaB activation by celecoxib, we evaluated combinations of irinotecan/MMC and irinotecan/MMC/celecoxib in patients with advanced solid malignancies