UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to TRADD

TRADD — TXN

Pathways - manually collected, often from reviews:

NCI Pathway Database TNF receptor signaling pathway : sTNF-alpha/TNFR1A/TRADD/TRAF2 complex (TNFRSF1A-TRADD-TRAF2-TNF) → TRX/ASK1 complex (MAP3K5-TXN) (modification, activates)
Ichijo et al., Science 1997, Saitoh et al., EMBO J 1998, Nishitoh et al., Mol Cell 1998
Evidence: mutant phenotype, physical interaction
NCI Pathway Database TNF receptor signaling pathway : sTNF-alpha/TNFR1A/TRADD/TRAF2 complex (TNFRSF1A-TRADD-TRAF2-TNF) → thioredoxin (TXN) (modification, activates) Ichijo et al., Science 1997, Saitoh et al., EMBO J 1998, Nishitoh et al., Mol Cell 1998
Evidence: mutant phenotype, physical interaction