Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — UVRAG

Text-mined interactions from Literome

Knævelsrud et al., Autophagy 2010 (Colonic Neoplasms...) : One such autophagic inducer is the Beclin 1 binding protein UVRAG , a positive regulator of the class III PI3K/Vps34 complex
Purpura et al., Oncotarget 2013 : In addition, KGFR induced a ligand dependent decrease of p63 through a miR-203 independent mechanism and this effect was blocked by inhibition of the PI3K/Akt signaling, which is the main pathway involved in KGFR dependent keratinocyte differentiation, suggesting that alterations of the KGFR/p63 crosstalk are responsible for the impairment of keratinocyte differentiation induced by 16E5 and that the opposite tumor-suppressive action of KGFR and oncogenic role of E5 might both involve p63