Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — VAV1

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Bertagnolo et al., Cell Signal 2004 : The Vav/p85 interaction is essential for the ATRA induced PI 3-K activity and for association of PI 3-K with actin, particularly in the nucleus
Bertagnolo et al., Exp Cell Res 2005 (Leukemia, Promyelocytic, Acute) : We have previously demonstrated that the amount and the tyrosine phosphorylation of Vav are up-regulated in both whole cells and nuclei of tumoral promyelocytes induced to granulocytic maturation by ATRA and that tyrosine phosphorylated Vav does not display any ATRA induced GEF activity but contributes to the regulation of PI 3-K activity
Vigorito et al., Cell Signal 2006 : These findings show that Vav proteins and PI3K regulation of PLCgamma contributes to the activation of PKD in response to BCR and or CD19 cross linking