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TCF24 — VHL
Text-mined interactions from Literome
Ivanova et al., J Mol Biol 2004
:
STRA13 is a
pVHL dependent bHLH
transcription factor up-regulated on the mRNA level in multiple cancer cell lines and implicated recently in the regulation of immune cell homeostasis and autoimmunity
Peruzzi et al., Proc Natl Acad Sci U S A 2006
(Carcinoma, Renal Cell...) :
VHL gene silencing in non-RCC renal epithelial cells phenotypically mimicked
VHL loss in RCC, and HGF-driven invasiveness was
blocked by the expression of a dominant negative mutant of
Tcf
Zehetner et al., Genes Dev 2008
:
von Hippel-Lindau (VHL) tumor suppressor protein, pVHL, negatively
regulates hypoxia-inducible factor HIF1alpha, a
transcription factor implicated in promoting a glycolytic form of metabolism
Shen et al., Cancer Discov 2011
(Carcinoma, Renal Cell...) :
pVHL inhibits the hypoxia-inducible
transcription factor ( HIF ), and HIF2a is a kidney cancer oncoprotein