Gene interactions and pathways from curated databases and text-mining

◀ Back to PRG4

PRG4 — WDR61

Text-mined interactions from Literome

Kowanko et al., Arthritis Rheum 1992 : PAF increased neutrophil mediated proteoglycan degradation in the 2-20 microM range ... In the absence of neutrophils, PAF ( 2-20 microM ) inhibited the synthesis of proteoglycan by bovine cartilage ... Neutrophils also inhibit proteoglycan synthesis, but PAF probably is not involved in this effect of neutrophils because the PAF receptor antagonists had no consistent effect ... PAF increases neutrophil mediated cartilage proteoglycan degradation in vitro ... PAF alone inhibits cartilage proteoglycan synthesis
Bustos et al., Clin Exp Immunol 1995 (Nephrosis) : CsA also reversed the inhibitory effect of PAF and TNF-alpha on proteoglycan synthesis