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WISP1 — WNT5A
Text-mined interactions from Literome
Price et al., J Am Coll Surg 2004
(Hyperplasia) :
Early induction of
WNT5A , coupled with the coordinated induction and repression of genes that modulate the Wnt signaling pathway,
led to the early, selective induction of
WISP1 and no other Wnt-inducible genes
Katoh et al., Int J Mol Med 2007
(Arthritis, Rheumatoid...) :
Canonical
WNT5A signaling through Frizzled and LRP5/LRP6 receptors
activates FGF20,
WISP1 , MYC and CCND1 transcription for the maintenance of stem/progenitor cells, while non-canonical WNT5A signaling through Frizzled and ROR2/PTK7/RYK receptors activates the RHOA, JNK, NLK and NFAT signaling cascades for the control of tissue polarity, cell adhesion or movement