Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — WNK1

Text-mined interactions from Literome

Parhar et al., Mol Cell Biochem 2007 : p65 ( Rel A ) Ser536 phosphorylation was not affected by the PI3K inhibitors but was dose-dependently attenuated by TPCK
Nakamura et al., Rheumatol Int 2007 (Sjogren's Syndrome) : Chemical inhibition of PI3K-Akt by LY294002/wortmannin did not affect EGF mediated NF-kappaB p65 nuclear translocation ; and NF-kappaB inhibition by Bay 11-7082 did not suppress Akt phosphorylation
Takeshima et al., BMC microbiology 2009 (Helicobacter Infections) : PI3K inhibitor suppressed H. pylori induced p65 phosphorylation and NF-kappaB transactivation, as well as interleukin-8 expression
Wang et al., J Biol Chem 2010 : Selective knockdown of EP2 or ectopic expression of EP3 blocks PKA- and PI3-K/Akt dependent p65 activation and markedly diminishes shear induced IL-6 expression