Gene interactions and pathways from curated databases and text-mining

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PIK3R1 — WNT4

Text-mined interactions from Literome

Sonderegger et al., Endocrinology 2010 : Chemical inhibition of PI3K abolished Wnt dependent phosphorylation of AKT and GSK-3beta and trophoblast motility but did not affect appearance of activated beta-catenin or Wnt/TCF reporter activity
Wang et al., J Bone Miner Res 2010 : T ( 3 ) -mediated Wnt-4 expression, beta-catenin activation, cell proliferation, and terminal differentiation of growth plate chondrocytes are partially prevented by the IGF1R inhibitor picropodophyllin as well as by the PI3K/Akt signaling inhibitors LY294002 and Akti1/2
Voskas et al., F1000 biology reports 2010 : Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling ?