Gene interactions and pathways from curated databases and text-mining

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HDAC2 — WNT5A

Text-mined interactions from Literome

Huh et al., J Biol Chem 2007 : HDAC inhibition promoted the expression of Wnt-5a , which is known to inhibit type II collagen expression, and knockdown of Wnt-5a blocked the ability of HDAC inhibitors to suppress type II collagen expression ... In addition, the induction of Wnt-5a expression by HDAC inhibitors was associated with acetylation of the Wnt-5a promoter
Li et al., Epigenetics 2012 (Colonic Neoplasms...) : However, histone deacetylase (HDAC) inhibitors trichostatin A (TSA) and sodium butyrate ( NaBt ) significantly increased Wnt5a mRNA expression in SW620 ... However, histone deacetylase (HDAC) inhibitors trichostatin A (TSA) and sodium butyrate ( NaBt ) significantly increased Wnt5a mRNA expression in SW620