hTreg-DS14702 hTreg-DS14702 Track Settings
 
hTreg-DS14702 DNaseI (per nucleotide)

Track collection: hTreg-DS14702

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     hTreg-DS14702  hTreg-DS14702 DNaseI per nt (observed)   Data format 
     hTreg-DS14702  hTreg-DS14702 DNaseI per nt (expected)   Data format 
Assembly: Human Dec. 2013 (GRCh38/hg38)

Description

De novo footprints identified in individual biosamples. This supertrack contains:
  • A multi-wig track of observed and expected per-nucleotide cleavages
  • Per nucleotide -log-transformed p-values of footprint statistic
  • Footprints delineated at various FDR thresholds

Display and configuration conventions

Per-nucleotide cleavage data is displayed as an overlay track -- observed cleavage counts are shown in blue and expected cleavabe counts are shown in yellow. The cleavage counts are not normalized (raw) to sequencing depth and the viewing limits may needed to be adjusted on a sample-by-sample and/or region-by-region basis.

Data availability

Footprint data is publically available at https://resources.altius.org/~jvierstra/projects/footprinting.2020 or ZENODO (DOI: 10.5281/zenodo.3603548).

Code and documentation available at GitHub and Read the docs.

Credits

This work was supported by NHGRI grant U54HG007010.

Please direct any questions/comments/inquiries to Jeff Vierstra (jvierstra@altius.org).

References

If you uses these data in your research, please cite:

Vierstra J et al.. Global reference mapping and dynamics of human transcription factor footprints. (2020) bioRxiv.