Description
Cancer Driver Log
is an expert-curated database of potentially actionable driver mutations for
molecular pathologists and laboratory directors to facilitate literature-based
annotation of genomic testing of tumors. The chromosome location and
all possible nucleotide positions, for each amino acid change, are shown
with associated literature reference.
The database was created by the Roychowdhury Lab Team at The Ohio State
University as an internal research resource for identifying
literature evidence of driver mutations in cancer, and their goal is to share
this information broadly for other translational cancer researchers to use.
Display conventions
Each entry of the database is shown.
This is very "sparse" track, with only 1800 features and a total genome coverage
of ~800 base pairs. The ten most annotated genes in this track are
(number of database entries in parentheses):
EGFR (144) FGFR4 (96) ERBB2 (93) FGFR2 (75) ERBB4 (72) ESR1 (72) JAK1 (72) KIT (72) IDH1 (63) AKT1 (60) JAK3 (60).
Data access
The database can be downloaded from the Cancer Driver Log.
References
| 
US Server