- Home
- Genomes
- Genome Browser
- Tools
- Mirrors
- Downloads
- My Data
- Projects
- Help
- About Us
STAT5b → Insulin: " Insulin selectively activates STAT5b , but not STAT5a, via a JAK2 independent signalling pathway in Kym-1 rhabdomyosarcoma cells "
STAT5 → JAK2: " Activation of STAT5 is typically mediated by JAK2 , but more recent data indicate a direct activation by the insulin receptor kinase "
STAT5b → insulin: " We here describe the selective tyrosine phosphorylation of STAT5b in Kym-1 cells in response to insulin "
STAT5b ⊣ insulin: " Blocking insulin signalling by HNMPA- ( AM ) ( 3 ), an insulin receptor kinase inhibitor, resulted in the loss of insulin induced STAT5b tyrosine phosphorylation, whereas the inhibition of JAK2 by the JAK selective inhibitor tyrphostin AG490 had no effect "
insulin receptor ⊣ insulin: " Blocking insulin signalling by HNMPA- ( AM ) ( 3 ), an insulin receptor kinase inhibitor , resulted in the loss of insulin induced STAT5b tyrosine phosphorylation, whereas the inhibition of JAK2 by the JAK selective inhibitor tyrphostin AG490 had no effect "
STAT5b → IFNgamma: " By contrast, in the same cells, IFNgamma induced STAT5b activation was JAK2 dependent, indicating that this signal pathway is functional in Kym-1 cells "
STAT5b → JAK2: " By contrast, in the same cells, IFNgamma induced STAT5b activation was JAK2 dependent , indicating that this signal pathway is functional in Kym-1 cells "