Gene interactions and pathways from curated databases and text-mining

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NFKB1 — PHKA2

Text-mined interactions from Literome

Shi et al., J Biol Chem 2001 : Placing PYK2 upstream of both PI3K and Akt activation, PYK2 activated Akt through a PI3K dependent pathway, and either a dominant negative form of Akt or the PI3K inhibitor LY294002 blocked PYK2 stimulated NF-kappa B-dependent transcription
Anand et al., Mol Immunol 2009 (MAP Kinase Signaling System...) : Inhibition of Pyk2 activity using a pharmacological inhibitor, Tyrphostin A9 significantly attenuated LPS induced Pyk2 tyrosine phosphorylation, p38 MAP kinase ( MAPK ) activation, NF-kappaB activation, and MCP-1 expression