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BMP6 — CDH1

Text-mined interactions from Literome

Yang et al., BMC cancer 2007 (Breast Neoplasms...) : BMP-6 promotes E-cadherin expression through repressing deltaEF1 in breast cancer cells ... Interestingly, ectopic expression of deltaEF1 was able to block BMP-6 induced transactivation of E-cadherin, whereas RNA interference mediated down-regulation of endogenous deltaEF1 in breast cancer cells abolished E-cadherin transactivation by BMP-6 ... We conclude that repression of deltaEF1 plays a key role in mediating BMP-6 induced transcriptional activation of E-cadherin in breast cancer cells
Park et al., Development 2010 : As BMP signaling also induces cadherin 6B expression and represses N-cadherin , cadherin regulated BMP signaling may create two opposing feedback loops
Helbing et al., J Pathol 2013 (Lung Injury) : Supporting this notion, pharmacological inhibition of BMP signalling by LDN193189 prevented reduction of E-cadherin and disruption of epithelial barrier function