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AOM — PTGS2

Text-mined interactions from Literome

Kishimoto et al., J Exp Clin Cancer Res 2002 (Colonic Neoplasms...) : In conclusion, AOM caused an increase in COX-2 and c-Myc mRNA expression, a decrease in APC mRNA expression, induction of apoptosis in normal appearing colonic mucosa, and a K-ras mutation in ACF with 4 or more crypts
Kwon et al., Scand J Gastroenterol 2007 (Colonic Neoplasms) : Interestingly, AOM did not affect COX-2 but decreased COX-1 expression in all ages
Fichera et al., J Surg Res 2007 (Adenocarcinoma...) : Compared with control, AOM/DSS significantly increased c-Myc ( 15-fold ), cyclooxygenase 2 (COX-2) ( 2.5-fold ), and pERK ( 10-fold ), and Ro26-2198 abolished these increases
Tammali et al., Carcinogenesis 2009 (Colonic Neoplasms...) : Furthermore, inhibition of AR or knockout of AR gene in the mice significantly prevented AOM induced expression of inducible nitric oxide synthase and cyclooxygenase-2 proteins as well as their messenger RNA
Ogawa et al., Cancer Sci 2012 (Colonic Neoplasms...) : The AOM induced increase in cyclooxygenase-2 mRNA expression in the colonic stroma was significantly decreased by EGCG
Singh et al., Cancer Res 1997 (Body Weight...) : The results indicate that AOM induced increasingly high levels of COX-2 expression with advancing stages of colon tumorigenesis ... HFCO further enhanced the AOM induced COX-2 expression