Lambertini et al., J Endocrinol 2002
(Osteoporosis) :
Double stranded DNA molecules, mimicking a regulatory region of the ER alpha gene promoter ( DNA-102 ) and acting as a ` silencer ' in breast cancer cells, were introduced into osteoblasts as ` decoy ' cis-elements to bind and functionally inactivate a putative negative transcription factor , and thus to induce ER alpha gene expression
Fearon et al., Cancer Cell 2003
(Breast Neoplasms) :
A recent paper in Cell ( Fujita et al., 2003 ) demonstrates that MTA3, a novel component of the Mi-2/NuRD transcriptional repression complex, is an estrogen receptor regulated inhibitor of the Snail zinc finger transcription factor in breast cancer
Held et al., Mol Cancer Res 2012
(Breast Neoplasms...) :
Phosphorylation of estrogen receptor-a ( ERa ) is critical for its transcription factor activity and may determine its predictive and therapeutic value as a biomarker for ERa positive breast cancers