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NA — NOS2
Text-mined interactions from Literome
Ilan et al., J Nutr 2005
:
NAC inhibited the reductions in eNOS and
iNOS transcription and protein levels
Lessio et al., Kidney Int 2005
:
We evaluated the
effect of CsA and the antioxidant
N-acetylcysteine (NAC) on
inducible nitric oxide synthase (iNOS) mRNA expression and nitric oxide synthesis, in rat renal artery vascular smooth muscle cells ( rVSMCs ) primary culture
Caglikulekci et al., J Invest Surg 2006
(Jaundice, Obstructive) :
NAC inhibits inducible
nitric oxide synthase , suppresses cytokine expression/release, and inhibits adhesion molecule expression and nuclear factor kappa B
Araki et al., J UOEH 2007
:
These results suggest that
NAC regulates
iNOS expression and NO production in adipocytes through the modulating activation of NF-kappa B
Wu et al., Free Radic Biol Med 2009
(MAP Kinase Signaling System) :
Activation of JNK and p38MAPK was weaker in TNFalpha plus PY-treated
NOS2 ( -/- ) mice and 1400W and
NAC blocked the activation of JNK and p38MAPK in wild-type mice
Pahan et al., Free Radic Biol Med 1998
:
Inhibition of LPS induced activation of NF-kappaB by NAC in rat peritoneal macrophages suggests that the inhibitory
effect of
NAC on the induction of
iNOS is due to the inhibition of NF-kappaB