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EDN1 — VEGFA
Text-mined interactions from Literome
Kozawa et al., Cell Signal 2000
(MAP Kinase Signaling System) :
Endothelin-1 induces
vascular endothelial growth factor synthesis in osteoblasts : involvement of p38 mitogen activated protein kinase
Zhong et al., Zhonghua Nei Ke Za Zhi 2001
(Anoxia...) :
To investigate the roles of the vascular endothelial growth factor ( VEGF ) and
endothelin-1(ET-1) in pulmonary vascular remodelling in rats with hypoxia induced pulmonary hypertension ( HPH ) and the
effect of pinacidil on
VEGF and ET-1 in rats with HPH
Spinella et al., J Biol Chem 2002
(Ovarian Neoplasms) :
Endothelin-1 induces
vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells
Qu et al., Bone 2006
:
Role of osterix in
endothelin-1 induced downregulation of
vascular endothelial growth factor in osteoblastic cells
Lee et al., Hypertens Pregnancy 2007
(Pre-Eclampsia) :
These findings suggest that
VEGF induced
endothelin-1 production might be mediated by MMP-2 rather than by ECE-1 upregulation
Saurina et al., Transplant Proc 2007
:
Endothelin-1 showed a decrease ( 8.1 +/- 3 to 5.2 +/- 1.1 pmol/L ; P = .1 ) and
VEGF in plasma
increased from 34.3 +/- 37 to 92.2 +/- 86 pg/mL ( P = .051 )
Virrey et al., Mol Cancer Ther 2010
(Brain Neoplasms...) :
DMC caused no apparent effects on the secretion of
vascular endothelial growth factor and interleukin-8 but
inhibited the secretion of
endothelin-1 in tumor associated EC
Papadopoulos et al., J Clin Hypertens (Greenwich) 2013
(Atherosclerosis...) :
Apelin is an adipokine that elicits endothelium dependent vasorelaxation and reduces arterial blood pressure, while relaxin is a protein hormone that induces the production of nitric oxide and
vascular endothelial growth factor and
inhibits endothelin and angiotensin II
Arkonac et al., J Biol Chem 1998
:
We found that platelet derived growth factor-BB ( PDGF-BB ) mRNA was also induced 3-fold after 5 h of VEGF stimulation, whereas neither
endothelin 1 nor transforming growth factor-beta1 was
regulated by
VEGF