Gene interactions and pathways from curated databases and text-mining

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CA2 — PSEN1

Text-mined interactions from Literome

Stutzmann et al., J Neurosci 2004 (Alzheimer Disease...) : Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability
McCombs et al., Molecular bioSystems 2010 : Using a genetically targeted sensor to investigate the role of presenilin-1 in ER Ca2+ levels and dynamics